In order to prevent and control the epidemic of COVID-19, documents issued by China indicates that protective face masks are required to use when performing aerosol-generating procedures (AGPs). However, it is not explicitly mention that which medical procedures can produce aerosol and whether the AGPs are associated with increased risk of infection transmission. Therefore, according to domestic and foreign guidelines and related literatures, this paper conducts literature review on aerosol, AGPs, high-risk medical procedures, and protection strategy.