A large number cases of novel coronavirus pneumonia have emerged in Wuhan and its surrounding areas, more than 10 000 health care workers(HCWs) national wide conduct medical rescue in Hubei Province. HCWs are at high risk of infection, preventing the infection spread in resident of medical team is a main point of the medical team. This paper discusses the management requirements, personal cleaning and disinfection, infection prevention and control in daily life, as well as environmental disinfection and air purification.