Effective prevention and control of novel coronavirus (2019-nCoV) outbreak is a serious challenge to the government, the public and each health professional. During the outbreak of 2019-nCoV, World Health Organization released "Advice on the use of masks in the community, during home care and in health care settings in the context of the novel coronavirus (2019-nCoV) outbreak", which provides instructional recommendations on the use of medical masks for public health and infection prevention and control professionals, health care managers, health care workers and community health workers. This article interprets the advice, puts forward suggestion on the wearing and management of medical masks in the community, during home care and in health care settings, aiming to provide scientific basis for rational and correct use of medical masks, avoiding unnecessary cost.