Fungal infection of bone and joint is a rare disease, but in recent years, due to the abuse of corticosteroids or other immunosuppressive agents, risk of such infection is increasing year by year. Fungal infection of bone and joint is undoubtedly a challenge for orthopedics. Based on domestic and foreign literatures, clinical characteristics as well as current diagnosis and treatment status of fungal arthritis are reviewed, so as to improve clinicians' understanding on the pathogenesis and related factors of fungal arthritis, and take positive and effective measures to strengthen the early diagnosis and treatment of fungal arthritis.