Non-tuberculous Mycobacteria exists widely in the environment. Due to medical water and equipment contamination, it can cause bloodstream, skin and soft tissue infection, even lead to infection outbreaks. In this paper, healthcare-associated infection (HAI) outbreaks of non-tuberculous Mycobacteria in foreign countries from 1985 to 2023 were summarized and analyzed by searching HAI outbreak-related literatures from PubMed, providing reference for the formulation and supervision of non-tuberculous Mycobacterium HAI prevention and control mea-sures in the future.