Abstract:Objective To investigate the nosocomial infection (NI) in patients in ICU, and analyse the risk factors and preventive measures. Methods The clinical data of all patients who were hospitalized between January 1, 2000 and December 31, 2002 were surveyed retrospectively. Results NI in patients in ICU was 19.69%, the case prevalence rate was 28.19%, the infection often occurred in patients with cerebral hemorrhage, cerebral infarction, cerebral laceration and contusion; lower respiratory tract infection was the most common infection (60.32%), the next was bacteremia; Gram-negative bacteria was the main pathogens causing NI (67.83%), most of which was Pseudomonas aeruginosa (34.78%), followed by fungi (17.39%). Conclusion The NI rate of ICU is higher than that of the other departments, the risk factors depend on the severity of underlying diseases, patients immunity status, invasive procedure and the quality of disinfection and sterilization.

Abstract:Objective To evaluate the isolation rate and antimicrobial resistance of nonfermenters causing nosocomial infection in ICU in a hospital. Methods The bacteria were identified by VITEK-AMS, and the antimicrobial susceptibility tests were done according to the disc agar diffusion methods. Results The isolation rate of nonfermenters in ICU was 38.36%, the most common bacterium was P.aeruginosa ( 18.75%), the next was A.baumannii ( 11.18%) and S.maltophilia ( 4.38%). The bacterial isolation rates were different among different sites, respiratory system and skin incision had the highest bacterial isolation rate, which was 65.40% and 51.23% respectively. P.aeruginosa, A.baumannii and S.maltophilia had high antimicrobial resistant rate. Conclusion The isolation rate of nonfermenters were rather high in the nosocomial infection in patients of ICU, the resistant rates of nonfermenters to the antimicrobials were high, the drugs for the treatment of the infection caused by nonfermenters should be chosen according to the result of the antimicrobial susceptibility test.