Abstract:

Abstract:Objective To investigate the high risk factors and effective prevention and control measures for infection in parturients and neonates with premature rupture of fetal membranes. Methods Medical records of patients with premature rupture of fetal membranes in a hospital from January 1999 to December 2002 were analyzed retrospectively. Results Forty-nine infection occurred among 1 416 ( 3.46%) inpatients. The constitutional ratio of genital tract infection in parturients was 32.26%, and incisional infection was 22.58%. The constitutional ratio of lower respiratory tract infection in neonates was 57.14%, and skin infection was 23.81%. Conclusion Premature rupture of fetal membranes is a high risk factor for infection in parturients and neonates. Preventive antimicrobial agents usage, early diagnosis of infection and timely termination of pregnancy are effective means to prevent infection caused by premature rupture of fetal membrane.

Abstract:

Abstract:目的 监测、分析目前常见酵母样真菌的耐药现状，以加强抗真菌药物的合理应用。方法 对某院2001年4月～2002年12月分离鉴定出的359株酵母样真菌，应用目前常用的10种抗真菌药物进行药物敏感试验和分析。结果 在10种抗真菌药物中，耐药率最高的是灰黄霉素(87．30％～100％)，其次为氟康唑(42．86％～54．96％)和伊曲康唑(28．57％～50．90％)。结论 当前临床常用抗真菌药的耐药菌株明显增多，特别是对氟康唑、伊曲康唑耐药率增高，应引起广大临床医师高度重视。