Objective To investigate routine maintenance of eye washer and emergency shower and the proficiency in operation process of health care workers(HCWs) in key departments of a hospital, so as to provide countermeasures for effective management. Methods From October 16 to 17, 2019, self-designed inspection form was used to investigate the integrity of eye washer and emergency shower in key departments of the hospital, HCWs were randomly selected to assess the operation process of eye washer and emergency shower, intervention measures were taken to solve the existing problems, investigation and assessment were conducted again one month later, results of two surveys and assessment were compared. Results There were 30 eye washers and 5 emergency showers in the whole hospital. After the implementation of intervention measures, the proportion of eye washer and emergency shower with low water pressure, high water pressure, facility damage, water leakage of sewer pipe, dirty facilities decreased compared with before the implementation of intervention measures, differences were all statistically signifi-cant (all P<0.05). The qualification rate of HCWs on the correct operation process of eye washer and emergency shower increased from 53.13% to 89.42% (P<0.05). Conclusion Effective management can improve the maintenance status and integrity rate of eye washer and emergency shower, and improve the emergency protection ability of HCWs in key departments.